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Fibrinogen That Appears in Bowman's Space of Proteinuric Kidneys in vivo Activates Podocyte Toll-Like Receptors 2 and 4 in vitro
Nephron: Experimental Nephrology, 11/03/09
Motojima M et al. – The results suggest that plasma macromolecules that appear in Bowman's space in proteinuric conditions have the capacity to induce podocyte cytokines through TLRs, and thereby accelerate podocyte injury.
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