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Osmolarity and partitioning of fluids
Anaesthesia & intensive care medicine, 11/02/09
Campbell I – Substances move down concentration gradients. When fluids are mixed together, they diffuse down their own concentration gradients and come to a dynamic equilibrium such that the concentrations of the various substances in all parts of the medium are the same. Water passes freely but the movement of solutes across the membrane, particularly charged molecules, is usually via a specific carrier protein. This may sometimes involve the expenditure of energy.
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