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Current Approaches to the Use of Sirolimus In Renal Transplantation
Transplantation Proceedings, 11/05/09
Kahan BD – Because of its inhibitory effects on endothelial and smooth muscle cell proliferation, sirolimus may be a useful tool to dampen chronic vasculo–obliterative processes that attenuate graft survival. With increasing experience with the drug, the true potential of sirolimus will be realized to be a critical element in the immunosuppressive matrix.
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