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See Latest ArticlesCystin Localizes to Primary Cilia via Membrane Microdomains and a Targeting Motif
Journal of the American Society of Nephrology, 10/26/09
Tao B et al. – The N–myristoylation signal is necessary but not sufficient to target cystin to the primary cilium. Analysis of deletion and chimeric constructs identified an AxEGG motif that is necessary to target and retain cystin in the cilium. Derangement of these localization motifs may lead to cystic kidney disease.
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Autosomal Dominant Polycystic Kidney Disease: New Treatment Options and How to Test Their Efficacy
Kidney and Blood Pressure Research, 11/06/09
The Role of the Mammalian Target Of Rapamycin (mTOR) in Renal Disease
Journal of the American Society of Nephrology, 11/04/09
Sirolimus Therapy for Patients With Adult Polycystic Kidney Disease: A Pilot Study
Transplantation Proceedings, 11/23/09
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