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See Latest ArticlesRenal Protection by Ischemic Preconditioning Is Associated with p50/p50 Homodimers
American Journal of Nephrology, 11/04/09
Cao C et al. – The investigation suggests that the general activity of NF–kB is attenuated in IPC kidneys, and the remaining activation of NF–kB is dominated with p50/p50 homodimer. Both of these effects might subsequently downregulate IL–18 expression, as well as provide renal protective effects of IPC. Though we focused on the phenomenological observations in this study, the detailed mechanism is still to be determined.
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