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Major role for ACE-independent intrarenal ANGII formation in type II diabetes
American Journal of Physiology: Renal Physiology, 10/27/09

Park S et al. – There is a switch from ACE–dependent to serine protease–dependent ANGII formation in the type II diabetic kidney. Pharmacological targeting of these serine protease–dependent pathways may provide further protection from diabetic renal vascular disease.

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