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Inhibition of NF-kB ameliorates sepsis-induced downregulation of aquaporin-2 / V2 receptor expression and acute renal failure in vivo
American Journal of Physiology: Renal Physiology, 10/15/09
Hocherl K et al. – The findings suggest that NF–kB activation is of importance for the downregulation of aquaporin–2 channel and vasopressin V2 receptor expression during sepsis. In addition, the data indicate that NF–kB inhibition ameliorates sepsis–induced acute renal failure.
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