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Genetic Silencing of Nox2 and Nox4 Reveals Differential Roles of These NADPH Oxidase Homologues in the Vasopressor and Dipsogenic Effects of Brain Angiotensin II
Hypertension, 10/12/09
Peterson JR et al. – The results demonstrate that both Nox2 and Nox4 are required for the full vasopressor effects of brain Ang–II but that only Nox2 is coupled to the Ang–II–induced water intake response. These studies establish the importance of both Nox2– and Nox4–containing NADPH oxidases in the actions of Ang–II in the central nervous system and are the first to reveal differential involvement of these Nox enzymes in the various physiological effects of central Ang–II.
Today in Basic Science/Genetics...keeping you current
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Mesenchymal Stem Cell Homing Capacity
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Today in Hypertension...keeping you current
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A selective endothelin-receptor antagonist to reduce blood pressure in patients with treatment-resistant hypertension: a randomised, double-blind, placebo-controlled trial
The Lancet, 10/27/09
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Pre-diabetes and arterial stiffness in uraemic patients
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