Nephrology Medical News about Indapamide Perindopril Diabetes Mellitus

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The ADVANCE Trial: Clarifying the Role of Perindopril/Indapamide Fixed-Dose Combination in the Reduction of Cardiovascular and Renal Events in Patients with Diabetes Mellitus
American Journal of Cardiovascular Drugs, 10/07/09

Waeber B et al. – The systematic use of a fixed–dose combination containing the ACE inhibitor perindopril and the diuretic indapamide afforded substantial protection against cardiovascular mortality and myocardial infarction, while providing important renoprotection, reducing the development of micro– and macroalbuminuria, and allowing regression of nephropathy. The beneficial effects were obtained regardless of baseline BP and whether or not the patients were receiving antihypertensive therapy.

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