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See Latest ArticlesThe role of glutathione S- transferase M1 and T1 gene polymorphisms and oxidative stress-related parameters in Egyptian patients with essential hypertension
European Journal of Internal Medicine , 10/01/09
Bessa SS et al. – GSTM1?ve/GSTT1?ve is a potential genetic factor to predict development of essential hypertension and permit early therapeutic intervention. The significant association between blood pressure and oxidative stress–related parameters indicates the pathogenic role of oxidative stress in hypertension. Antioxidants could be useful in the management of essential hypertension to prevent progressive deterioration and target organ damage however, further studies involving long–term clinical trials may help to assess the efficacy of these therapeutic agents.
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