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Glucocorticoids and body fat associated with renal uric acid and oxalate, but not calcium excretion, in healthy children
Metabolism-Clinical and Experimental, 10/13/09
Shi L et al. – Body fatness and potentially bioactive free glucocorticoids (even in the physiologic range) appear to affect urinary excretion rates of oxalate and uric acid, whereas urinary calcium output is more strongly related to dietary factors in healthy children. The data provide the first in vivo–based evidence that the obesity– or hypercortisolism–associated urolithiasis may be a pathophysiologic continuation of the corresponding endocrine metabolic variations in healthy children.
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