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See Latest ArticlesGlucose Depletion Enhances Sensitivity to Shear Stress-induced Mechanical Damage in Red Blood Cells by Rotary Blood Pumps
Artificial Organs, 10/02/09
Sakota D et al. – The shear stress increases metabolism of RBCs consuming more energy ATP which is produced anaerobically from glycolytic process. Hence, in the closed circuit testing of rotary blood pumps, depletion of glucose might occur after prolonged pumping, which in turn affects metabolic process of RBCs by changing their size, shape, and morphology. It is thus suggested to monitor and control the glucose level of the fluid that suspends RBCs depending on the study duration.
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