Nephrology Medical News about beta-catenin signaling

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DH9, a novel PPARgamma agonist suppresses the proliferation of ADPKD epithelial cells: An association with an inhibition of beta-catenin signaling
Investigational New Drugs, 10/08/09

Liu M et al. – The effect of DH9 on cell proliferation was mediated by a PPARgamma independent mechanism. Since DH9 decreased the levels of beta–catenin in cells via a GSK3beta mediated degradation pathway, this acts as a mechanism for growth inhibition by DH9.

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Nonstructural 5A protein activates beta-catenin signaling cascades: Implication of hepatitis C virus-induced liver pathogenesis
Journal of Hepatology, 11/04/09 Relevance Score: 65%

Role of Adenosine Signaling in Penile Erection and Erectile Disorders
The Journal of Sexual Medicine, 11/05/09 Relevance Score: 45%

Regulation of Gastric B Cell Recruitment Is Dependent on IL-17 Receptor A Signaling in a Model of Chronic Bacterial Infection
Journal of Immunology, 10/21/09 Relevance Score: 45%

Toll-like receptor signaling in airborne Burkholderia thailandensis infection
Infection and Immunity, 10/12/09 Relevance Score: 45%

Neurotrophin signaling through tropomyosin receptor kinases contributes to survival and proliferation of non-Hodgkin lymphoma
Experimental Hematology, 10/22/09 Relevance Score: 44%