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Outcomes of antiproteinuric RAAS blockade: High-dose compared with dual therapy
Current Hypertension Reports, 09/23/09
Tobe SW et al. – Therapy for patients with nephropathy should include treatment with the maximum recommended doses of an ACE inhibitor or ARB in addition to lowering blood pressure to target. For patients with overt nephropathy, more research is required on the role of dual therapy or supramaximal dosing to reduce hard renal and cardiovascular outcomes. Practitioners using either of these strategies to manage proteinuria should monitor their patients carefully.
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