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Colchicine treatment in autosomal dominant polycystic kidney disease: Many points in common
Medical Hypotheses, 09/25/09
Solak Y et al. – Indirect evidence also support our hypothesis, in which taxol and paclitaxel, other two microtubule inhibitors, were shown to delay cyst formation in experimental models of ADPKD. Despite its narrow therapeutic index, widespread experience makes colchicine a suitable candidate for prolonged clinical use, should experimental studies show any benefit in ADPKD.
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Autosomal Dominant Polycystic Kidney Disease: New Treatment Options and How to Test Their Efficacy
Kidney and Blood Pressure Research, 11/06/09
The Role of the Mammalian Target Of Rapamycin (mTOR) in Renal Disease
Journal of the American Society of Nephrology, 11/04/09
Sirolimus Therapy for Patients With Adult Polycystic Kidney Disease: A Pilot Study
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