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See Latest ArticlesBradykinin induces the formation of vesicle-like structures containing vinculin and PtdIns(4,5)P2 in renal papillary collecting duct cells
American Journal of Physiology: Renal Physiology, 09/18/09
Marquez MG et al. – The present study, which was carried out under physiological conditions with cells that were not genetically manipulated, show for the first time that BK induces the formation of vesicle–like structures containing vinculin and PtdIns(4,5)P2, which transport vinculin to the site of FA assembly. Therefore, the modulation of the formation of these vesicle–like structures could be a physiological mechanism through which the cell can reuse the BK–induced internalized vinculin to be delivered for newly forming FAs in renal papillary collecting duct cells.
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