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See Latest ArticlesUse of Warfarin in People with Low Glomerular Filtration Rate or on Dialysis
Seminars in Dialysis, 09/11/09
Holden RM et al. – Trials of low–intensity anticoagulation for people with grafts and of fixed 1 mg daily warfarin dosing in people with catheters showed no benefit. Warfarin substantially increases the risk of bleeding in patients on dialysis. It is possible that it may contribute also to accelerated vascular calcification. Large randomized studies are needed to assess the risk–benefit ratio of warfarin in people with low GFR or on dialysis for a range of indications.
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