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See Latest ArticlesClinical usefulness of a prognostic score in histological analysis of renal biopsy in patients with lupus nephritis
Journal of Rheumatology, 09/22/09
Kojo S et al. –These results demonstrate the advantage of our prognostic score compared to subclasses in predicting the renal outcome of class IV patients.
Methods- Retrospective analysis of 99 biopsy-proven subjects with lupus nephritis from 1990 to 2006 performed using new classification
- Each histological lesion evaluated by multivariate survival analysis as predictive factor for renal insufficiency
- Independent predictors graded to develop prognostic score based on regression coefficient
- Receiver operating-characteristic curve based on prognostic score plotted to determine the most appropriate cutoff point
- IV-G group tended to exhibit worse renal outcome compared with the IV-S group
- Difference not significant
- Predictors of poor renal outcome were extracapillary proliferation, glomerular sclerosis, and fibrous crescents
- Predictors of favorable renal outcome were hyaline thrombi and fibrous adhesions
Today in Glomerular/Tubular Dz...keeping you current
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Mycophenolate mofetil and intravenous cyclophosphamide are similar as induction therapy for class V lupus nephritis
Kidney International, 11/05/09
Change in Estimated GFR Associates with Coronary Heart Disease and Mortality
Journal of the American Society of Nephrology, 11/23/09
Biomarkers for Lupus Nephritis: The Quest Continues
Clinical Journal of the American Society of Nephrology, 11/13/09
Today in Radiology/Diagnostics...keeping you current
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Systematic Review: Sodium Bicarbonate Treatment Regimens for the Prevention of Contrast-Induced Nephropathy
Annals of Internal Medicine, 11/03/09
Eosinophil Count Is Positively Correlated with Albumin Excretion Rate in Men with Type 2 Diabetes
Clinical Journal of the American Society of Nephrology, 11/05/09
Biomarkers for Lupus Nephritis: The Quest Continues
Clinical Journal of the American Society of Nephrology, 11/13/09
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