Nephrology Medical News about tubular damage

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Urinary excretion of carnitine as a marker of proximal tubular damage associated with platin-based antineoplastic drugs
Nephrology Dialysis Transplantation, 09/10/09

Haschke M et al. – All platin derivatives investigated are associated with renal tubular damage in humans without significantly affecting glomerular function. The rapid onset and complete reversibility of this effect favour a functional mechanism such as impaired expression of OCTN2 in proximal tubular cells.

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Tubular Toxicity in Sirolimus- and Cyclosporine-Based Transplant Immunosuppression Strategies: An Ancillary Study From a Randomized Controlled Trial
American Journal of Kidney Diseases, 11/19/09 Relevance Score: 68%

Inhibitors of histone deacetylases suppress cisplatin-induced p53 activation and apoptosis in renal tubular cells
American Journal of Physiology: Renal Physiology, 11/12/09 Relevance Score: 66%

Cardiopulmonary Bypass Priming Using a High Dose of a Balanced Hydroxyethyl Starch Versus an Albumin-Based Priming Strategy
Anesthesia & Analgesia, 11/19/09 Relevance Score: 64%

Complement Activation and Progression of Chronic Kidney Disease
Hong Kong Journal of Nephrology, 10/07/09 Relevance Score: 64%

High frequencies of diabetic micro- and macroangiopathies in patients with type 2 diabetes mellitus with decreased estimated glomerular filtration rate and normoalbuminuria
Nephrology Dialysis Transplantation, 11/16/09 Relevance Score: 63%