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Rapid deterioration of renal function in a patient with multiple myeloma associated with amyloid and light chain depositions
Clinical and Experimental Nephrology, 09/09/09
Nakayama N et al. – Slight amyloid depositions in the mesangium and vessels, and massive granular electron–dense deposits and deposition of monoclonal light chain lambda in renal basement membranes and vessels were found, indicating the rare condition of co–existence of amyloidosis and light chain deposition disease (LCDD). The rapid progression of renal failure may have been caused by massive deposition of monoclonal light chains in the patient.
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