Nephrology Medical News about Diabetes Insipidus

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Biased Agonist Pharmacochaperones of the AVP V2 Receptor May Treat Congenital Nephrogenic Diabetes Insipidus
Journal of the American Society of Nephrology, 09/08/09

Jean–Alphonse F et al. – The molecules displayed original functionally selective properties (biased agonism) toward the hV2R, being unable to recruit arrestin, trigger receptor internalization, or stimulate mitogen–activated protein kinases. These characteristics make these hV2R agonist pharmacochaperones promising therapeutic candidates for cNDI.

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Autosomal recessive familial neurohypophyseal diabetes insipidus - onset in early infancy
European Journal of Endocrinology, 11/10/09 Relevance Score: 67%

Diverse Vasopressin V2 Receptor Functionality Underlying Partial Congenital Nephrogenic Diabetes Insipidus
American Journal of Physiology: Renal Physiology, 10/08/09 Relevance Score: 65%

Vasopressin Type 2 Receptor V88M Mutation: Molecular Basis of Partial and Complete Nephrogenic Diabetes Insipidus
Nephron: Physiology, 10/08/09 Relevance Score: 65%

Study: Intervention raises costs for diabetes
Medical Economics, 10/21/09 Relevance Score: 64%

Challenges in management of patients with intracranial germ cell tumor and diabetes insipidus treated with cisplatin and/or ifosfamide based chemotherapy
Journal of Neuro-Oncology, 10/14/09 Relevance Score: 64%