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Dilated cardiomyopathy with hypertension: prevalence and response to high-dose (beta)1-adrenoceptor antagonist therapy
Clinical and Experimental Pharmacology and Physiology, 09/10/09
Zeng X et al. – DCM patients have a higher prevalence of hypertension than the general population. Patients in the DCM–H subgroup were characterized by a higher resting HR and a family history of hypertension and were more tolerant of and more responsive to metoprolol treatment. These data suggest that this subgroup of DCM patients could have higher sympathetic nerve activity and is suitable for treatment with a higher dose of metoprolol.
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