Nephrology Medical News about everolimus

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Role of everolimus in the treatment of renal cell carcinoma
Therapeutics and Clinical Risk Management, 08/31/09

George S et al. – The double–blind, randomized, placebo–controlled phase III trial of everolimus (RECORD–1) conducted in MRCC patients after progression on sunitinib or sorafenib, or both, demonstrated a progression–free survival benefit favoring the study drug. Everolimus thus established itself as a standard of care in the second–line setting for patients with MRCC who have failed treatment with VEGF receptor inhibitors.

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Conversion from a calcineurin inhibitor to everolimus therapy in maintenance liver transplant recipients: A prospective, randomized, multicenter trial
Liver Transplantation, 10/01/09 Relevance Score: 87%

Effects of Everolimus on Cytokines, Oxidative Stress, and Renal Histology in Ischemia-Reperfusion Injury of the Kidney
Renal Failure, 10/26/09 Relevance Score: 85%

Abbotts XIENCE PRIME and XIENCE V Receive Indications in Europe for Treatment of Patients with Diabetes
Abbott, 11/03/09 Relevance Score: 84%

Downregulation of 18F-FDG Uptake in PET as an Early Pharmacodynamic Effect in Treatment of Non–Small Cell Lung Cancer with the mTOR Inhibitor Everolimus
The Journal of Nuclear Medicine, 11/02/09 Relevance Score: 83%

Everolimus But Not Mycophenolate Mofetil Therapy Is Associated With Soluble HLA-G Expression in Heart Transplant Patients
The Journal of Heart and Lung Transplantation, 10/28/09 Relevance Score: 80%