Nephrology Medical News about Sirolimus

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Morales JM et al. – When compared with continuous SRL–CsA–ST, CsA withdrawal at 3 months followed by SRL–ST significantly improved glomerular filtration rate (GFR) and blood pressure without a further increase in lipid parameters or an incidence of untoward effects from hyperlipidemia, despite a 2–fold higher SRL exposure.

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A Phase I Study of the Mammalian Target of Rapamycin Inhibitor Sirolimus and MEC Chemotherapy in Relapsed and Refractory Acute Myelogenous Leukemia
Clinical Cancer Research, 10/26/09 Relevance Score: 88%

Current Approaches to the Use of Sirolimus In Renal Transplantation
Transplantation Proceedings, 11/05/09 Relevance Score: 87%

Combined treatment with cisplatin and sirolimus to enhance cell death in human mesothelioma
The Journal of Thoracic and Cardiovascular Surgery, 10/27/09 Relevance Score: 87%

Multiple coronary artery aneurysm formation one year and four years after sirolimus-eluting coronary stent implantation
Cardiovascular Revascularization Medicine, 10/16/09 Relevance Score: 84%

Resolution of late sirolimus-eluting stent thrombosis after tirofiban treatment
Heart and Vessels, 10/07/09 Relevance Score: 84%