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See Latest ArticlesSevelamer Hydrochloride Use and Circulating Endotoxin in Hemodialysis Patients: A Pilot Cross-Sectional Study
Journal of Renal Nutrition, 08/31/09
Sun PP et al. – This proof–of–concept pilot study demonstrates that the use of sevelamer hydrochloride is associated with a lower plasma endotoxin level, supporting the hypothesis that this agent binds to endotoxin in the intestinal lumen. Although this may be an important mechanism by which sevelamer hydrochloride attenuates systemic inflammation, a clinical trial is required to test this hypothesis.
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