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Szeto CC et al. – The G–137C polymorphism of the IL–18 promoter is associated with the cardiovascular mortality, and a trend of association with all–cause mortality, in patients with diabetic nephropathy. The association, however, becomes insignificant after adjusting for confounding factors. Further studies are needed to test other genetic determinants of the association between systemic inflammation and cardiovascular disease in renal failure patients.

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