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See Latest ArticlesPathogenetic features of severe segmental lupus nephritis
Nephrology Dialysis Transplantation, 08/25/09
Behara VY et al. – The findings in DPGN involve a classic immune complex–mediated glomerulonephritis as demonstrated by the abundant immune aggregates witnessed in the peripheral capillary wall. In contrast, a paucity of peripheral immune aggregates is seen in SSGN implying a different pathogenesis. The data support a mechanism of glomerular injury in SSGN that is separate from the generally accepted unitary concept of immune complex deposition in lupus nephritis.
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