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Activation of the epithelial Na+ channel (ENaC) in the collecting duct by vasopressin contributes to water reabsorption
American Journal of Physiology: Renal Physiology, 08/21/09
Bugaj V et al. – The results demonstrate a quantitatively important action of vasopressin on ENaC suggesting that distal nephron Na+ reabsorption mediated by this channel contributes to maintenance of water reabsorption. In addition, the results support that the combined actions of vasopressin and aldosterone are required to achieve maximally activated ENaC.
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