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See Latest ArticlesContribution of Endothelin 1 to the Vascular Effects of Diesel Exhaust Inhalation in Humans
Hypertension, 08/20/09
Langrish JP et al. – Diesel exhaust inhalation increases vascular sensitivity to ET–1 and reduces vasodilatation to ETA receptor antagonism despite unchanged plasma ET–1 concentrations. Given the tonic interaction between the ET and NO systems, we conclude that diesel exhaust inhalation alters vascular reactivity to ET–1 probably through its effects on NO bioavailability.
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