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Glomerular filtration barrier
Current Opinion in Nephrology and Hypertension, 08/18/09

Haraldsson B et al. – Glomerular diseases account for 90% of chronic kidney disease requiring dialysis and transplantation at an annual cost of $20 billion in the USA. In clinical practice, we lack specific treatment of these diseases, giving us plenty of room for improvement. Research should be directed toward deeper understanding of the signaling pathways involved in different conditions of proteinuria, the cross–talk between cell types in the glomerulus, and the identification of novel targets for treatment of acquired kidney disease.

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