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Podocyte polarity signalling
Current Opinion in Nephrology and Hypertension, 08/18/09
Simons M et al. – Accumulating evidence indicates that conserved polarity protein complexes are essential for normal podocyte morphology and differentiation. The diseased podocyte, which typically presents with foot process effacement, might require these molecular guideposts when recovering from stress and when restoring normal podocyte morphology.
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