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See Latest ArticlesShould diuretics always be included as initial antihypertensive management in early-stage CKD
Current Opinion in Nephrology and Hypertension, 08/12/09
Segura J et al. – Extracellular volume expansion is an important, if not the most important, contributing factor to hypertension seen in chronic kidney disease. Protection against progression of renal dysfunction has two main requirements: strict blood pressure control and lowering proteinuria to values as near to normal as possible. Diuretics have been a useful tool to manage volume overload and to achieve strict blood pressure control in patients with chronic kidney disease. Albeit other blood pressure–lowering agents offer additional favorable effects independently of blood pressure changes, diuretics will continue to be used in these patients.
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