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Effect of the cGMP pathway on AQP2 expression and translocation: potential implications for nephrogenic diabetes insipidus
Nephrology Dialysis Transplantation, 08/12/09
Boone M et al. – The results suggest that while activators of the cGMP pathway are likely beneficial in the treatment of X–linked NDI, their ability to relieve NDI in the patients may be improved when combined with agents stimulating AQP2 expression.
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