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See Latest ArticlesAntineoplastic effect of proliferation signal inhibitors: from biology to clinical application
Journal of Nephrology, 08/07/09
Bertoni E et al. – The deregulations permit the survival, growth, proliferation and migration of cancer cells and promote tumor angiogenesis. Targeting them has been a successful anticancer strategy. Targeting mTOR as well as these deregulated pathways could provide enhanced anticancer activity. The efficacy of mTOR inhibitors in preventing several types of cancers in transplanted patients or in recovering cancers developed in transplant patients has been documented in both trials and single reports.
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Efficacy and safety of pazopanib in patients with metastatic renal cell carcinoma
Journal of Clinical Oncology, 12/18/09
Renal cell carcinoma with caval involvement: Contemporary strategies of surgical treatment
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Antiproliferative and apoptosis inducing effects of indirubin-3'-monoxime in renal cell cancer cells
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