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Medical Therapy to Facilitate the Passage of Stones: What Is the Evidence
European Urology, 08/07/09
Seitz C et al. – Pooled analyses suggest that MET with alpha–blockers or calcium channel blockers augments stone expulsion rates, reduces the time to stone expulsion, and lowers analgesia requirements for ureteral stones with and without ESWL for stones <10 mm. There is some evidence that a combination of alpha–blockers and corticosteroids might be more effective than treatment with alpha–blockers alone. Renal stones after ESWL also seem to profit from MET. The vast majority of randomised studies incorporated into the present systematic review are small, single–centre studies, limiting the strength of conclusions.
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