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Clinical and Immunologic Effects of Intranodal Autologous Tumor Lysate-Dendritic Cell Vaccine with Aldesleukin (Interleukin 2) and IFN-2a Therapy in Metastatic Renal Cell Carcinoma Patients
Clinical Cancer Research, 08/04/09
Schwaab T et al. – The clinical and immunologic responses observed in this trial suggest an interaction between DC vaccination and cytokine therapy. The data support the hypothesis that modulation of inflammatory, regulatory, and angiogenic pathways are necessary to optimize therapeutic benefit in renal cell carcinoma patients.
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