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See Latest ArticlesGlomerular Epithelial Cell Injury Associated with Mutant -Actinin-4
American Journal of Physiology: Renal Physiology, 08/05/09
Cybulsky AV et al. – ER stress was associated with aggregation and ubiquitination of alpha–actinin–4 K256E, and impairment of the ubiquitin–proteasome system. In addition, alpha–actinin–4 K256E exacerbated apoptosis in the context of mild proteasome inhibition. Thus, alpha–actinin–4 K256E triggers several metabolic abnormalities, which may lead to GEC injury and glomerulosclerosis.
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Association of High Pretransplant sIL-6R Plasma Levels with Acute Tubular Necrosis in Kidney Graft Recipients
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American Journal of Nephrology, 12/17/09
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