Nephrology Medical News about Renin secretion

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The role of calcium in the regulation of renin secretion
American Journal of Physiology: Renal Physiology, 08/05/09

Beierwaltes WH – While cAMP is the dominant second messenger for renin secretion, calcium appears to modulate the integrated activities of the enzymes which balance cAMP synthesis and degradation. Thus, this review concludes that calcium modifies the amplitude of cAMP–mediated renin signaling pathways. While calcium does not directly control renin secretion, increased calcium inhibits and decreased calcium amplifies cAMP–stimulated renin secretion.

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Journal of Virology, 10/12/09 Relevance Score: 43%