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Plasma pyrophosphate and vascular calcification in chronic kidney disease
Nephrology Dialysis Transplantation, 07/27/09
O’Neill WC et al. – Plasma PPi is negatively associated with vascular calcification in end–stage renal disease (ESRD) and CKD but is not affected by dialysis, the mode of dialysis or nutritional or inflammatory status. Although these data are consistent with an inhibitory effect of PPi on vascular calcification, further studies are needed to establish a causal role.
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