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Haemolytic uraemic syndrome caused by factor H mutation: is single kidney transplantation under intensive plasmatherapy an option
Nephrology Dialysis Transplantation, 07/27/09
Hirt–Minkowski P et al. – Complement factor H (CFH) mutation is one of the causes of atypical haemolytic uraemic syndrome (aHUS). Patients with CFH mutation–associated aHUS progress often to end–stage renal disease despite plasma exchange therapy. The authors report a case of successful single kidney allograft transplantation in a patient with a CFH gene mutation (R1210C), who had end–stage renal failure after three flares of aHUS treated with plasma exchange.
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