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See Latest ArticlesUrinary NGAL Marks Cystic Disease in HIV-Associated Nephropathy
Journal of the American Society of Nephrology, 07/24/09
Paragas N et al. – Nephrosis and a rapid decline in kidney function characterize HIV–associated nephropathy (HIVAN). Histologically, HIVAN is a collapsing focal segmental glomerulosclerosis with prominent tubular damage. Marked upregulation of NGAL accompanies HIVAN and support further study of uNGAL levels in large cohorts to aid in the noninvasive diagnosis of HIVAN and screen for HIVAN–related tubular damage.
Jonathan Barasch, 07/24/09
| The pattern of expression of NGAL is localized. This differs from ischemic or septic patterns. |
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