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(Click the title below to leave the MDLinx Network and go to the Journal's Website)

Lawrentschuk N et al. – Intratumoral hypoxia does exist within a human RCC xenograft model using invasive oxygen probe measurements. 124I–cG250 targets RCC with correlation between uptake on noninvasive PET–CT studies and traditional biodistribution studies opening the possibility of using PET/CT in future studies. Finally, CAIX expression was not related to hypoxia in this model, supporting the hypothesis that cell lines may subvert known hypoxia mechanisms in hypoxic environments.


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