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Delay in onset of metabolic alkalosis during regional citrate anti-coagulation in continous renal replacement therapy with calcium-free replacement solution
Annals of Cardiac Anaesthesia, 07/15/09
See KC et al. - Continuous renal replacement therapy (CRRT) is a commonly used modality for treatment of acute kidney injury in the intensive care unit (ICU). It involves connecting the patient to an extra-corporeal circuit that allows blood to flow, through a hemofilter, thereby modulating fluid, solute, and acid-base balance. A calcium-free replacement solution may be beneficial in avoiding metabolic alkalosis and reduce the use of citrate during anti-coagulation.
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Systematic Review: Sodium Bicarbonate Treatment Regimens for the Prevention of Contrast-Induced Nephropathy
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