Nephrology Medical News about Cellular VEGF Bioactivity

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The Importance of Cellular VEGF Bioactivity in the Development of Glomerular Disease
Nephron: Experimental Nephrology, 07/13/09

Foster RR - The bioactivity of glomerular VEGF (or activity of available VEGF) is critical to the physiological maintenance of the glomerular filtration barrier. Disturbances in glomerular VEGF expression have been linked to numerous glomerulopathies, highlighting its importance in disease progression within the kidney. However, the changes in expression are not consistent between conditions; enhanced expression sometimes appears to have a renoprotective effect, yet at other times it appears destructive.

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