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Akt1 mediates purinergic-dependent NOS3 activation in thick ascending limbs
American Journal of Physiology: Renal Physiology, 07/06/09
Silva GB et al. - Extracellular ATP regulates many physiological processes via release of nitric oxide (NO). ATP stimulates NO in thick ascending limbs (TALs), but the signaling cascade involved in the cells of this nephron segment, as well as many other types of cells, is poorly understood.
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