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See Latest ArticlesActivation of AMP-activated kinase as a strategy for managing autosomal dominant polycystic kidney disease
Medical Hypotheses, 07/07/09
McCarty MF et al. - Recent research has established that AMP-activated kinase (AMPK) can suppress the activity of each of these proteins. Clinical AMPK activators such as metformin and berberine may thus have potential in the clinical management of ADPKD. The traditional use of berberine in diarrhea associated with bacterial infections may reflect, in part, the inhibitory impact of AMPK on chloride extrusion by small intestinal enterocytes.
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Autosomal Dominant Polycystic Kidney Disease: New Treatment Options and How to Test Their Efficacy
Kidney and Blood Pressure Research, 11/06/09
The Role of the Mammalian Target Of Rapamycin (mTOR) in Renal Disease
Journal of the American Society of Nephrology, 11/04/09
Sirolimus Therapy for Patients With Adult Polycystic Kidney Disease: A Pilot Study
Transplantation Proceedings, 11/23/09
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