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High Weight Differences between Donor and Recipient Affect Early Kidney Graft Function — A Role for Enhanced IL-6 Signaling
American Journal of Transplantation, 07/08/09
Gong W et al. - The frequency of delayed function of kidney transplants varies greatly and is associated with quality of graft, donor age and the duration of cold ischemia time. Furthermore, body weight differences between donor and recipient can affect primary graft function, but the underlying mechanism is poorly understood. We transplanted kidney grafts from commensurate body weight (L-WD) or reduced body weight (H-WD) donor rats into syngeneic or allogeneic recipients.
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