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Red Blood Cell Damage from Extracorporeal Circulation in Hemodialysis
Seminars in Dialysis, 06/29/09
Polaschegg H-D - Blood damage is an unavoidable side effect of extracorporeal circulation. Acute hemolysis is caused by obstructions within the extracorporeal circuit caused by manufacturing errors, kinking of blood tubing or user errors, or by a combination of excessive flow and improper cannula or catheter dimensions. The risk of acute hemolysis can be further reduced by industrial quality control, better design of dialysis equipment, and hemodialysis machine control. Adverse effects caused by chronic mechanical hemolysis need to be studied.
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