Your Article Summary
See Latest ArticlesRenin, prorenin and the kidney: a new chapter in an old saga
Journal of Nephrology, 07/02/09
Ichihara A et al. - The binding of prorenin to the (pro)renin receptor triggers 2 major pathways: a nonproteolytic conformational change in prorenin to its active form (angiotensin II-dependent pathway) and an intracellular pathway via the (pro)renin receptor itself (angiotensin II-independent pathway). In diabetic animals, an increased plasma prorenin level not only causes the generation of angiotensin II via the angiotensin II-dependent pathway, it also stimulates the (pro)renin receptor’s own intracellular signaling pathway in a manner that is independent of the generated angiotensin II.
Today in Basic Science/Genetics...keeping you current
Receive free subspecialty "5-minute updates" via email
A family with X-linked benign familial hematuria
Pediatric Nephrology, 12/01/09
Tacrolimus enhances transforming growth factor-[beta]1 expression and promotes tumor progression
Transplantation, 12/01/09
OCRL1 function in renal epithelial membrane traffic
American Journal of Physiology: Renal Physiology, 11/30/09
Today in Endocrinology...keeping you current
Receive free subspecialty "5-minute updates" via email
Response of Secondary Hyperparathyroidism to Cinacalcet Depends on Parathyroid Size
Nephron: Clinical Practice, 12/01/09
Stone composition and metabolic status
Urological Research - Urolithiasis, 11/25/09
A Trial of Darbepoetin Alfa in Type 2 Diabetes and Chronic Kidney Disease
New England Journal of Medicine, 11/20/09