Nephrology Medical News about prorenin

Become a Member Today!
Register

Most Viewed Abstracts

1. Report Shows Shift in Starting Salaries for Physicians

2. 2008 Exclusive Survey—Earnings: Good news for primary care income

3. Medicare pay-for-reporting effort draws fire from frustrated doctors

4. Allopurinol-induced recurrent dress syndrome: Pathophysiology and treatment

5. Debunking Myths in the US Healthcare System

Your Article Summary

See Latest Articles

(Click the title below to leave the MDLinx Network and go to the Journal's Website)

Renin, prorenin and the kidney: a new chapter in an old saga
Journal of Nephrology, 07/02/09

Ichihara A et al. - The binding of prorenin to the (pro)renin receptor triggers 2 major pathways: a nonproteolytic conformational change in prorenin to its active form (angiotensin II-dependent pathway) and an intracellular pathway via the (pro)renin receptor itself (angiotensin II-independent pathway). In diabetic animals, an increased plasma prorenin level not only causes the generation of angiotensin II via the angiotensin II-dependent pathway, it also stimulates the (pro)renin receptor’s own intracellular signaling pathway in a manner that is independent of the generated angiotensin II.

<< Previous
Methodological considerations for observational studies of acute...

Next >>
Digital ischaemia and mitral stenosis due to calcification in a...